De Novo meningitis caused by Propionibacterium acnes in a patient with metastatic melanoma.

Determination of antibiotic susceptibility and Minimum Inhibitory Concentration (MIC) of the Propionibacterium acnes to the prevalent antibiotics in the treatment of Acne vulgaris

ABSTRACTPropionibacterium acnes is propounded as one of the significant factors in occurrence of acne. Today, due to development of the antibiotic resistance, most of the acne treatments are faced with failure. In order to determine the antibiotic resistance of the P.acnes strains isolated from the patients with acne, this research has been carried out. 70 samples collected using microbial cult...

بررسی اثر ضد میکروبی عصاره‌ی اتانولی برگ درخت گردو بر روی پروپیونی باکتریوم آکنه

Background and Objective: Acne is one of the medical problems and propionibacterium acnes is the pathogenic agent that has received a considerable attention. Different parts of Juglans regia have been shown to have antibacterial activity on many bacteria. Its leaves have antioxidant property and if it shows antibacterial effect on propionibacterium acnes, it might be an alternative drug for the...

A de novo Reciprocal X; 9 Translocation in A Patient with Premature Ovarian Failure

Increased Cytotoxicity of Cisplatin in SK-MEL 28 Melanoma Cells upon Down-Regulation of Melanoma Inhibitor of Apoptosis Protein

Background: Malignant melanoma is a highly metastatic cutaneous cancer and typically refractory to chemotherapy. Deregulated apoptosis has been identified as a major cause of cancer drug resistance, and upregulated expression of the inhibitor of apoptosis protein melanom, an inhibitor of apoptosis (ML-IAP) is frequent in melanoma. Methods: Based on the conclusion that ML-IAP expression contribu...

Intratumoral Injection of Propionibacterium acnes Suppresses Malignant Melanoma by Enhancing Th1 Immune Responses

Malignant melanoma (MM) is an aggressive cutaneous malignancy associated with poor prognosis; many putatively therapeutic agents have been administered, but with mostly unsuccessful results. Propionibacterium acnes (P. acnes) is an aerotolerant anaerobic gram-positive bacteria that causes acne and inflammation. After being engulfed and processed by phagocytes, P. acnes induces a strong Th1-type...